Adequate plasma drug concentrations suggest that amoxicillin can be administered by continuous infusion using elastomeric pumps
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منابع مشابه
Identification of drug combinations administered by continuous subcutaneous infusion that require analysis for compatibility and stability
BACKGROUND A continuous subcutaneous infusion (CSCI) delivered via syringe pump is a method of drug administration used to maintain symptom control when a patient is no longer able to tolerate oral medication. Several classes of drugs, such as opioids, antiemetics, anticholinergics, antipsychotics and benzodiazepines are routinely administered by CSCI alone or in combinations. Previous studies ...
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To the Editor: Over recent years, invasive hypertension treatments have led to a new clinical condition, called device-resistant hypertension (DRH).1 DRH is defined as blood pressure (BP) >140/90 mm Hg, with at least 3 antihypertensives at maximal doses, including a diuretic,2 without BP decrease after the invasive treatments. These patients are not infrequent and are obliged to visit several h...
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Ceftazidime is a beta-lactam compound that exerts a time-dependent bactericidal effect. Numerous arguments are in favor of continuous administration of ceftazidime, both for reasons of clinical efficacy and to preserve bacteriological mutation. We report a prospective, single-center, parallel-group, randomized, controlled trial comparing two modes of administration of ceftazidime, namely, conti...
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Cephalotaxine alkaloids have been extensively used in the Peoples Republic of China for treatment of acute leukemias and solid tumors (Yu-hua, L., Shu-fen, G., Fu-ying, Z., Shu-zhi, X., and Hui-lin, Z. Chin. Med. J., 96: 303-305, 1983). Several Phase I trials of homoharringtonine have been completed in the United States using either bolus administration or continuous infusion over a 5-day perio...
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Currently available cyanide antidotes must be given by intravenous injection over 5-10 min, making them ill-suited for treating many people in the field, as could occur in a major fire, an industrial accident, or a terrorist attack. These scenarios call for a drug that can be given quickly, e.g., by intramuscular injection. We have shown that aquohydroxocobinamide is a potent cyanide antidote i...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2017
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/dkx178